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At a Glance

The Health Department has developed a webpage to help you track the number of monkeypox cases and vaccine availability in Philadelphia. This webpage will be updated every Monday.

Topic Priority Date of Alert
Jynneos Eligibility Update Update Sep 1, 2022
Tecovirimat Treatment for Monkeypox Update Aug 22, 2022
Monkeypox Vaccination Update: Intradermal Injection Recommended Advisory Aug 18, 2022
Monkeypox Vaccination Strategy and Prioritization of First Doses Advisory Aug 4, 2022
Pain Management Recommendations for Monkeypox Update Aug 2, 2022


Clinical presentation in the current outbreak has been atypical and often there is no prodrome. All patients have been found to have a skin rash upon physical examination, however the rash is often not scattered and is instead limited to one body site. Lymphadenopathy has not been universal during the current outbreak.

Key epidemiologic risk factors have included (1) contact with a person or people with a similar appearing rash or a diagnosis of monkeypox and (2) close or intimate contact with people in a social network experiencing monkeypox activity (e.g., men who have sex with men and transgender persons who have sex with men who meet partners through an online website, digital app, or social event).

Worldwide Surveillance Data from the CDC

Vaccine Information

The Health Department has begun vaccinating Philadelphians who are at high-risk. Currently, clinics are being offered on a rolling, invitation-only basis. Individuals who believe that they are at a high risk of being exposed to monkeypox can call the Call Center at 215-685-5488 to see if they are eligible to be vaccinated.

To be eligible, people must meet all of the following conditions:

  • Gay, bisexual, transgender, or other men who have sex with men and/or transgender, gender non-conforming, or non-binary persons; AND
  • Meet ONE of the following criteria:
    • Have had multiple or anonymous sex partners in the last 14 days
    • Have had a newly diagnosed STI in the past 12 months, including gonorrhea, chlamydia, early syphilis, or HIV
    • Have recently attended or plan to attend any venue where anonymous sex or sex with multiple partners will occur (e.g. saunas, bathhouses, sex clubs, sex parties) in the next 30 days
    • Have met recent partners or plan to meet new partners in the next 30 days through social media platforms (such as Grindr, Tinder, or Scruff), or at clubs, raves, sex parties, or saunas

Additionally, the following people are eligible:

  • Sex workers (of any sex or gender), AND/OR
  • Anyone with known close contact (skin-to-skin) with someone with monkeypox in the past 14 days

The eligibility criteria has been established based on who may be at the highest-risk of exposure to monkeypox. As more vaccine is delivered, more people will be invited to these vaccine clinics.

While the vaccine is normally a 2-dose series, the Department of Public Health is currently only administering one dose to patients due to the limited supply of the vaccine. One dose still provides some protection against monkeypox and provides the opportunity to provide vaccine to more individuals who may be at high-risk of contracting monkeypox.

More information on Philadelphia's monkeypox response can be found on the City of Philadelphia's webpage.

Diagnosis & Management

The following should be considered for management of suspected cases:

  • Place the patient in a private examination room as soon as possible and make sure to keep the door closed.
  • Provide the patient with a surgical mask to wear and a sheet or gown to cover lesions on exposed skin.
  • Personnel collecting specimens should use PPE, including gowns, gloves, an N95 respiratory or equivalent, and eye protection. Maintain documentation of staff who have contact with the patient.

Testing is available through commercial laboratories (including LabCorp, Quest, and Mayo Clinic) as well as through the Pennsylvania Department of Health's Bureau of Laboratories (PADOH BOL). For additional details about the testing procedures for each lab, please refer to this document: Monkeypox Virus Testing Procedures For Labs

Providers should:

  • Consider testing for alternate etiologies, including STIs as well as viral and bacterial infections.
  • Advise patients under investigation for monkeypox who are not hospitalized and are awaiting results to isolate at home until PDPH provides further guidance.


For Healthcare Providers:

PDPH Resources

CDC Resources

  • The Centers for Disease Control and Prevention (CDC) recently conducted a Clinical Outreach and Communication Activity (COCA) call that provided updated information on the clinical diagnosis and treatment of monkeypox. Clinicians are highly encouraged to watch the recording for further information regarding recognition and testing of monkeypox including clinical case studies and photos from the current outbreak.
  • The CDC will be hosting another COCA call on Tuesday, July 26 to provide additional updates on the epidemiology of the monkeypox outbreak, commercial testing capacity, how to obtain and use TPOXX (tecovirimat) to treat monkeypox, and vaccine strategy,

For Patients and Community Members:

There are no patient or community resources for Monkeypox.


There are no posters for Monkeypox.