Health Information Portal (HIP)

Carbapenemase-producing Organisms (CPO)

Topic	Priority Priority Alert Conveys the highest level of importance; warrants immediate action or attention. Advisory Provides important information for a specific incident or situation; may not require immediate action. Notification Provides information regarding an incident or situation; unlikely to require immediate action. Update Provides updated information regarding an incident or situation; unlikely to require immediate action.	Date of Alert
Update to Drug-Resistant Organism Reporting Requirements in Philadelphia Concerning Carbapenem-resistant Organisms	Update	Sep 26, 2025
New Drug-Resistant Organism Reporting Requirements in Philadelphia	Advisory	Apr 25, 2018

Surveillance

CDC Carbapenemase-producing Organisms (CPO) Case Definition

CDC National CRE Tracking

Vaccine Information

There is no vaccine information available for Carbapenemase-producing Organisms (CPO).

Diagnosis & Management

CDC Laboratory Resources for HAIs

CDC Information About CREs for Health Professionals

Reporting to PDPH

Report CPO cases to the Philadelphia Department of Public Health by calling 215-685-6748 during business hours or completing the CPO Report Form (PDF) and fax to 215-238-6947.

• PDPH CPO Reporting FAQ (PDF)

Guidance for Management and Control

Healthcare Facilities

• PDPH CPO Checklist for LTCFs (PDF)

Resources

For Healthcare Providers:

• PDPH Infection Prevention Symposium (2014): Antimicrobial Stewardship and Carbapenem-resistant Enterobacteriaceae
• CDC Threat Report: Antibiotic Resistance Threats in the United States (2019)
• CDC Vital Signs Report: Carbapenem-resistant Enterobacteriaceae (MMWR, March 8, 2013 / 62(09);165-170)

For Patients and Community Members:

Posters:

There are no posters for Carbapenemase-producing Organisms (CPO).