Health Information Portal (HIP)

Carbapenemase-Producing Organisms (CPO)

Topic	Priority Priority Alert Conveys the highest level of importance; warrants immediate action or attention. Advisory Provides important information for a specific incident or situation; may not require immediate action. Notification Provides information regarding an incident or situation; unlikely to require immediate action. Update Provides updated information regarding an incident or situation; unlikely to require immediate action.	Date of Alert
Update to Drug-Resistant Organism Reporting Requirements in Philadelphia Concerning Carbapenem-resistant Organisms	Update	Sep 26, 2025
New Carbapenem-Resistant Enterobacteriaceae Warrant Action by Healthcare Providers	Advisory	Apr 8, 2013

Surveillance

• Carbapenem-producing Organisms (CPO) Case Definition [CDC]
• National CRE Tracking [CDC]

Vaccine Information

There is no vaccine information available for Carbapenemase-Producing Organisms (CPO).

Diagnosis & Management

• Laboratory Resources for HAIs [CDC]
• CRE Information of Health Professionals [CDC]

Resources

For Healthcare Providers:

Reporting to PDPH

Report CPO cases to the Philadelphia Department of Public Health by calling 215-685-6748 during business hours or completing and faxing the CPO Patient Report Form below to 215-238-6947.

• CPO Reporting Form
• CPO Reporting FAQ [PDPH, 2025]

CPO Guidelines

Healthcare Facilities

• LTCF Checklist [PDPH, 2025]

Links & Resources

• PDPH Infection Prevention Symposium: Antimicrobial Stewardship and Carbapenem-Resistant Enterobacteriaceae [PDPH, 2014]
• CDC Threat Report: Antibiotic Resistance Threats in the United States [CDC, 2019]
• CDC Vital Signs Report: Carbapenem-Resistant Enterobacteriaceae [MMWR, March 8, 2013 / 62(09);165-170]

For Patients and Community Members:

Posters:

There are no posters for Carbapenemase-Producing Organisms (CPO).